Acute kidney injury, chronic kidney disease each a risk of the other

Acute kidney injury (AKI) and chronic kidney disease (CKD) are closely intertwined, with each disease a risk factor for developing the other and sharing other risk factors in common, as well as sharing causes for the diseases to get worse, and outcomes, sugges...

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Osteopontin Is a Strong Predictor of Incipient Diabetic Nephropathy, Cardiovascular Disease, and All-Cause Mortality in Patients With Type 1 Diabetes.

OBJECTIVE: Osteopontin (OPN) is a multifunctional protein suggested to be a player in the arterial disease of patients with type 2 diabetes. However, its role for complications in patients with type 1 diabetes (T1D) is unknown. We therefore investigated the as...

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Treasure trove of genes key to kidney cancer revealed by research

Their study, in the journal Oncotarget, is the most extensive analysis to date of gene expression’s role in ccRCC tumor growth and metastasis. The ccRCC subtype accounts for 80 percent of all kidney cancer cases. This study is a thorough analysis, becaus...

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Top News for PKD Research

Sunday, June 29th, 2014 Researchers continue to make important and sometimes surprising discoveries about PKD and the PKD1 gene. Here is a roundup of the latest PKD findings. A University of Colorado School of Medicine study has shown that pravastatin can slow...

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Cellular Signaling Responsible for Kidney Regeneration Discovered

Sunday, June 29th, 2014 With their exciting discovery of the cellular signaling responsible for renal regeneration, scientists from Sheba Medical Center, Tel Aviv University, and Stanford University aim to change the way researchers think about kidneys. Using ...

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Small changes to US kidney allocation policy may help reduce geographic disparities in transplantation

Small changes to kidney allocation policies in the United States could help alleviate geographic disparities related to transplantation, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). ...

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Risk factors for chronic kidney disease are present decades before diagnosis

Risk factors for chronic kidney disease (CKD) are present and identifiable 30 years before diagnosis, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings suggest avenues for future resea...

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‘Big data’ technique improves monitoring of kidney transplant patients

A new data analysis technique radically improves monitoring of kidney patients, according to a University of Leeds-led study, and could lead to profound changes in the way we understand our health. The research, published in the journal PLoS Computational Biol...

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Important differences in hospitalization rates among racial, ethnic groups on dialysis

There are significant racial and ethnic differences in hospitalization rates among kidney failure patients on dialysis, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). The differences a...

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Assessment of vascular function in patients with chronic kidney disease.

Patients with chronic kidney disease (CKD) have significantly increased risk of cardiovascular disease (CVD) compared to the general population, and this is only partially explained by traditional CVD risk factors. Vascular dysfunction is an important non-trad...

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